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10.1016/J.FITOTE.2011.10.001 133 YangC

Assessing ssris' effects on fetal cardiomyocytes utilizing placenta-fetus model

The electron transport chain, a series of protein complexes within the mitochondria that produce ATP, becomes inefficient and "leaky." Instead of producing energy, these damaged mitochondria leak excessive amounts of superoxide radicals into the cell, further amplifying oxidative stress

SARS-CoV-2 encodes ORF9b, a small accessory protein that localizes to mitochondria, interacts with translocase of the outer membrane (TOM70), and impedes MAVS-dependent signaling (Gao et al., 2021